Non-Alcoholic Steatohepatitis (NASH)

Nonalcoholic steatohepatitis (NASH) is liver inflammation caused by a buildup of fat in the liver. The fat buildup is not caused by drinking alcohol.
 
Many people have a buildup of fat in the liver, and for most people it causes no symptoms and no problems. However, in some people the fat causes inflammation of the liver. Due to the inflammation, the liver doesn’t work as well as it should.
 
NASH can get worse and cause scarring of the liver, which leads to cirrhosis. But the disease does not always get worse.
 
There is no clear reason why some people with excess fat in the liver develop NASH and others do not.

Quick Facts

Symptoms:

NASH is usually a silent disease with few or no symptoms.
 
As NASH progresses and liver damage gets worse, you may start to have symptoms such as:

Common Causes:

Although NASH has become more common, its underlying cause is still not clear. It’s most likely caused by a combination of your family history and things in your environment.
 
Risk factors are things that make a health problem more likely. Risk factors for NASH and liver damage include:

Diagnosis:

  • Medical history review and review of symptoms
  • Physical examination
  • Blood test panels
  • Imaging studies (abdominal ultrasound, CT scan, MRI scan)
  • Liver biopsy

Common Treatment:

There is currently no specific therapies for NASH. Recommendations may include:
  • Reduce weight
  • Follow a balanced and healthy diet
  • Increase physical activity
  • Avoid alcohol
  • Avoid unnecessary medications

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